Checkpoint Kinase (Chk) compound (inhibitors, antagonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-45427	Prexasertib CHK1 inhibitor	Prexasertib (LY-2606368) is a potent, selective, ATP-competitive inhibitor of CHK1 with Ki of 0.9 nM.
PC-44037	LY2603618 CHK1 inhibitor	Rabusertib (LY2603618) is a potent and selective small molecule inhibitor of Chk1 (IC50= 7 nM).
PC-42769	AZD-7762 Chk1/Chk2 inhibitor	AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM.
PC-44033	CCT241533 hydrochloride Chk2 inhibitor	CCT241533 hydrochloride is a potent and selective ATP-competitive inhibitor of CHK2 with IC50 of 3 nM.
PC-44032	CCT241533 Chk2 inhibitor	CCT241533 is a potent and selective ATP-competitive inhibitor of CHK2 with IC50 of 3 nM.
PC-45429	CCT-244747 CHK1 inhibitor	CCT-244747 (CCT244747) is a potent, highly selective, orally active, ATP competitive CHK1 inhibitor with biochemical IC50 of 8 nM.
PC-45574	CCT-245737 CHK1 inhibitor	CCT-245737 (SRA-737) is a highly potent, selective, ATP-competitive inhibitor of Chk1 with IC50 of 1.3 nM.
PC-21172	2OH-BNPP1 BUB1 inhibitor	2OH-BNPP1 is a small molecule inhibitor of BUB1 (budding uninhibited by benzimidazoles-1) kinase, abrogates TGFβ signaling.

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