AZD-7762 |CAS:860352-01-8 Probechem Biochemicals

Chemical Structure : AZD-7762

CAS No.: 860352-01-8

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AZD-7762 (AZD7762;AZD 7762)

货号: PC-42769Not For Human Use, Lab Use Only.

AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1880	In stock
50 mg	￥2980	In stock
100 mg		Get quote

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生物&药学活性

AZD-7762 (AZD7762) is a potent and selective inhibitor of Chk1/2 with IC50 of 5 nM.
AZD-7762 shows less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.
AZD-7762 enhances the radiosensitivity of mutated p53 tumor cell lines and HT29 xenografts.

物理化学性质&存储条件

分子量	362.4218
分子式	C17H19FN4O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Thiophenecarboxamide, 3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-

参考文献

1. Zabludoff SD, et al. Mol Cancer Ther. 2008 Sep;7(9):2955-66.

2. Mitchell JB, et al. Clin Cancer Res. 2010 Apr 1;16(7):2076-84.

3. Morgan MA, et al. Cancer Res. 2010 Jun 15;70(12):4972-81.

AZD-7762 (AZD7762;AZD 7762)

生物&药学活性

物理化学性质&存储条件

参考文献

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AZD-7762 (AZD7762;AZD 7762)

生物&药学活性

物理化学性质&存储条件

参考文献

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