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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Checkpoint Kinase (Chk)-ML367
ML367

Chemical Structure : ML367

CAS No.: 381168-77-0

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ML367 (ML-367)

货号: PC-26494Not For Human Use, Lab Use Only.

ML367 is a small molecule inhibitor of ATAD5 stabilization with IC50 of 1.2 uM, blocks general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation.

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10 mg ￥780 In stock
25 mg ￥1280 In stock
50 mg ￥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML367 is a small molecule inhibitor of ATAD5 stabilization with IC50 of 1.2 uM, blocks general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation.

物理化学性质&存储条件

分子量 334.33
分子式 C19H12F2N4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3,4-Difluorophenyl)-2-(pyridin-4-yl)quinazolin-4-amine

参考文献

1. Rohde JM, et al. 2013 Apr 15 [updated 2013 Nov 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet].

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