| Cat. No. |
Product Name |
Information |
| PC-27815 |
IMD-1
AChE/BChE inhibitor
|
IMD-1 is a potent dual inhibitor of acetylcholine and butyrylcholine esterases (AChE and BChE) with IC50 of 34.6 nM and 49.04 nM, protects SH-SY5Y cells against H2O2-induced oxidative injury by modulating oxidative stress, mitochondrial dysfunction, inflammatory mediator release, and apoptosis-related responses. |
| PC-23391 |
Donepezil
AChE inhibitor
|
Donepezil (E2020) is a potent, specific acetylcholinesterase (AChE) inhibitor with IC50 of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively. |
| PC-49073 |
VP15 hydrochloride
AChE inhibitor
|
VP15 hydrochloride (VP-15 HCl) is a BBB-penetrant, orally active, multitarget directed ligand against acetylcholine and monoamine oxidase enzymes with IC50 of 0.04 and 0.37 uM for AChE and MAO-B, respectively, >600-fold selectivity over BuChE. |
| PC-63361 |
Zanapezil
AChE inhibitor
|
Zanapezil (TAK-147) is a potent, selective acetylcholinesterase (AChE) inhibitor with IC50 of 97.7 nM. |
| PC-62461 |
Ipidacrine
AChE inhibitor
|
Ipidacrine is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
| PC-62460 |
Ipidacrine hydrochloride
AChE inhibitor
|
Ipidacrine hydrochloride is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. |
| PC-61036 |
TAK-802 hydrochloride
AChE inhibitor
|
TAK-802 hydrochloride is a potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM. |
| PC-61035 |
TAK-802
AChE inhibitor
|
TAK-802 is potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM. |
| PC-60066 |
AD-35
AChE inhibitor
|
AD-35 is a donepezil analog that can moderately inhibit acetylcholinesterase and metal-induced Aβ aggregation in vitro and shows disassembly of Aβ aggregates. |
| PC-42789 |
Rivastigmine tartrate
AChE inhibitor
|
Rivastigmine tartrate (ENA-713, SDZ ENA-713) is an acetylcholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. |
| PC-45188 |
Rivastigmine
AChE inhibitor
|
Rivastigmine is an acetylcholinesterase (AChE) inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase. |
| PC-45211 |
(±)-Huperzine A
AChE inhibitor
|
(±)-Huperzine A is a naturally occurring sesquiterpene alkaloid that a reversible and selective inhibitor of acetylcholinesterase (AChE). |
