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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Acetylcholinesterase (AChE)-Ipidacrine
Ipidacrine

Chemical Structure : Ipidacrine

CAS No.: 118499-70-0

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Ipidacrine (Amiridine, NIK 247)

货号: PC-62461Not For Human Use, Lab Use Only.

Ipidacrine is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.

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500 mg ￥580 In stock
1 g ￥880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ipidacrine is a reversible acetylcholinesterase (AChE) inhibitor that directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels.
Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.

物理化学性质&存储条件

分子量 188.27
分子式 C12H16N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine

参考文献

1. Nabeshima T, et al. Eur J Pharmacol. 1988 Sep 23;154(3):263-9.

2. Onodera K, et al. Nihon Shinkei Seishin Yakurigaku Zasshi. 1998 Apr;18(2):33-7.

3. Kojima J, et al. Gen Pharmacol. 1998 Aug;31(2):297-300.

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