IMD-1

Chemical Structure : IMD-1

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货号: PC-27815Not For Human Use, Lab Use Only.

IMD-1 is a potent dual inhibitor of acetylcholine and butyrylcholine esterases (AChE and BChE) with IC50 of 34.6 nM and 49.04 nM, protects SH-SY5Y cells against H2O2-induced oxidative injury by modulating oxidative stress, mitochondrial dysfunction, inflammatory mediator release, and apoptosis-related responses.

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生物&药学活性

IMD-1 is a potent dual inhibitor of acetylcholine and butyrylcholine esterases (AChE and BChE) with IC50 of 34.6 nM and 49.04 nM, protects SH-SY5Y cells against H2O2-induced oxidative injury by modulating oxidative stress, mitochondrial dysfunction, inflammatory mediator release, and apoptosis-related responses.

物理化学性质&存储条件

分子量	280.28
分子式	C16H12N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4-hydroxyphenyl) (4-(4-hydroxyphenyl)-1H-imidazole-2-yl) methanone

参考文献

1. Burak Kuzu, et al. Bioorg Chem. 2019 May:86:187-196.

2. Derya-Andeden M, et al. Neurochem Res. 2026 Aug 12;51(4):236.

IMD-1

生物&药学活性

物理化学性质&存储条件

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IMD-1

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物理化学性质&存储条件

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