mGluR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-22899	LY379268 mGlu2/3 agonist	LY379268 is a potent, selective group II metabotropic glutamate (mGlu) receptor agonist with Ki of 40.6 nM and 4.7 nM, EC50 of 3.91 nM and 7.63 nM for mGlu2 and mGlu3, respectively.
PC-22270	XAP044 mGlu7 antagonist	XAP044 is a potent, selective antagonist of metabotropic glutamate receptor subtype 7 (mGlu7), inhibits lateral amygdala long term potentiation (LTP) in brain slices with IC50 of 88 nM.
PC-22231	VU0361737 mGluR4 PAM	VU0361737 (ML128) is a potent, selective positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4) with EC50 of 240 nM and 110 nM for human and rat mGluR4 receptors, respectively.
PC-22230	VU0155041 mGluR4 PAM	VU0155041 is a potent, selective positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4) with EC50 of 798 and 693 nM at human and rat mGluR4, respectively.

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