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首页-小分子抑制剂&激动剂-GPCR-mGluR-VU0092273
VU0092273

Chemical Structure : VU0092273

CAS No.: 393110-43-5

VU0092273

货号: PC-22907Not For Human Use, Lab Use Only.

VU0092273 is a potent mGlu5 positive allosteric modulator (PAM) with an EC50 of 0.27 uM, binds to the MPEP site.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VU0092273 is a potent mGlu5 positive allosteric modulator (PAM) with an EC50 of 0.27 uM, binds to the MPEP site.

物理化学性质&存储条件

分子量 305.38
分子式 C20H19NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4-hydroxypiperidin-1-yl)(4-(phenylethynyl)phenyl)methanone

参考文献

1. Rodriguez AL, et al. Mol Pharmacol. 2010 Dec;78(6):1105-23.

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