ML337 | mGlu3 NAM | Probechem Biochemicals

Chemical Structure : ML337

CAS No.: 1443118-44-2

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货号: PC-22905Not For Human Use, Lab Use Only.

ML337 is a potent, selective and brain-penetrant negative allosteric modulator of mGlu3 with IC50 of 593 nM, with no effect on mGlu2 (IC50>30 uM).

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ML337 is a potent, selective and brain-penetrant negative allosteric modulator of mGlu3 with IC50 of 593 nM, with no effect on mGlu2 (IC50>30 uM).

分子量	353.39
分子式	C21H20FNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl][(3R)-3-hydroxy-1-piperidinyl]methanone

1. Wenthur CJ, et al. J Med Chem. 2013 Jun 27;56(12):5208-12.