| Cat. No. |
Product Name |
Information |
| PC-35689 |
GSK2646264
Syk inhibitor
|
GSK2646264 (GSK-2646264) is a potent, selective Spleen Tyrosine Kinase (Syk) inhibitor with pIC50 of 7.1, >300-fold selectivity over Autota B. |
| PC-63503 |
TAS05567
Syk inhibitor
|
TAS05567 (TAS-5567) is a novel potent, selective, orally available Spleen tyrosine kinase (Syk) inhibitor with IC50 of 0.37 nM. |
| PC-63376 |
GSK143
Syk inhibitor
|
GSK143 is a highly potent, selective, orally efficacious Syk inhibitor with pIC50 of 7.5, >600-fold selective over ZAP-70. |
| PC-43350 |
R788 disodium hexahydrate
Syk inhibitor
|
Fostamatinib (R788) is a prodrug of the active metabolite R406, which is a potent, ATP-competitive inhibitor of Syk kinase with Ki/IC50 of 30/41 nM. |
| PC-43349 |
Fostamatinib
Syk inhibitor
|
Fostamatinib (R788) is a prodrug of the active metabolite R406, which is a potent, ATP-competitive inhibitor of Syk kinase with Ki/IC50 of 30/41 nM. |
| PC-43348 |
R788 disodium salt
Syk inhibitor
|
Fostamatinib (R788 disodium salt) is a prodrug of the active metabolite R406, which is a potent, ATP-competitive inhibitor of Syk kinase with Ki/IC50 of 30/41 nM. |
| PC-42880 |
R406
Syk inhibitor
|
R406 is a potent, specific and orally available Syk kinase inhibitor with Ic50 of 41 nM, inhibits anti-IgE-mediated CHMC degranulation with EC50 of 56 nM. |
| PC-42815 |
R406 free base
Syk inhibitor
|
R406 (Tamatinib) free base is a potent, specific and orally available Syk kinase inhibitor with Ic50 of 41 nM, inhibits anti-IgE-mediated CHMC degranulation with EC50 of 56 nM. |
| PC-63137 |
BAY 61-3606 hydrochloride
Syk inhibitor
|
BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM, displays no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
| PC-63130 |
JTE-852
Syk inhibitor
|
JTE-852 is a novel potent, selective, ATP-competitive Syk kinase inhibitor with IC50 of 1.25/1.28 nM for human/rat Syk, respectively. |
| PC-63126 |
ASN-002
SYK/JAK inhibitor
|
ASN-002 (Gusacitinib, ASN002) is a novel and potent dual inhibitor of SYK/JAK kinases with IC50 of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively, in biochemical assays. |
| PC-62789 |
Syk-IN-23
Syk inhibitor
|
Syk-IN-23 is a potent, selective Syk kinase inhibitor with IC50 of 20 nM, possesses good PK in both rat and dog and demonstrated efficacy in rat CIA model. |
