| Cat. No. |
Product Name |
Information |
| PC-49800 |
Toosendanin
Hck/Lyn inhibitor
|
Toosendanin is a small-molecule compound that blocks macrophage-mediated immunosuppression and activates T cells by inhibiting Hck and Lyn kinases, reprograms macrophages to enforce antitumor immunity in glioblastoma (GBM). |
| PC-38544 |
Squarunkin A
UNC119-Src inhibitor
|
Squarunkin A is a small molecule UNC119-cargo interaction inhibitor, selectively inhibits the binding of the N-terminus of Src kinase to UNC119A with IC50 of 10 nM. |
| PC-73124 |
CH6953755
YES1 inhibitor
|
CH6953755 (CH 6953755) is a potent, selective, orally available YES1 kinase inhibitor with IC50 of 1.8 nM. |
| PC-72678 |
iHCK-37
Hck inhibitor
|
iHCK-37 (ASN05260065) is a potent and selective Hck inhibitor with Ki of 0.22 uM. |
| PC-72224 |
DGY-06-116
SRC inhibitor
|
DGY-06-116 (SRC inhibitor 15a) is a potent, selective, covalent Src inhibitor (biochemical IC50=3 nM) that taregrs a P-Loop cysteine (Cys277). |
| PC-72223 |
SM1-71
Multikinase inhibitor
|
SM1-71 is a multi-targeted acrylamide-modified inhibitor that covalently inhibits 23 kinases including MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC (IC50=4 nM), YES1, FGFR1 (IC50=54 nM), ZAK (MLTK), MAP3K1, LIMK1 and RSK2. |
| PC-36164 |
UNC119-Src interaction inhibitor 3
UNC119-Src inhibitor
|
UNC119-Src interaction inhibitor 3 is a potent, specific small molecule inhibitor of UNC119-Src interaction with IC50 of 12 nM for displacement of the Src peptide from UNC119A. |
| PC-35754 |
RK-20449
Hck inhibitor
|
RK-20449 (A419259) is a potent, small molecule inhibitor of hematopoietic cell kinase (HCK) with IC50 of 0.43 nM. |
| PC-35738 |
Lck inhibitor C8863
Lck inhibitor
|
Lck inhibitor C8863 (C8863, RK-24466, KIN 001-51) is a potent, selective Lck inhibitor, inhibits Lck (64-509) and LckCD isoforms with IC50 of <1 nM and < 2 nM. |
| PC-35102 |
TL02-59
Fgr kinase inhibitor
|
TL02-59 is a potent, selective, orally available inhibitor of Src-family kinase Fgr IC50 of 0.03 nM, also inhibits Lyn and Hck with IC50 of 0.1 and 160 nM, respectively. |
| PC-63531 |
KX2-361
Src/tubulin inhibitor
|
KX2-361 (KX 02) is a potent, orally active dual Src signaling/tubulin polymerization inhibitor, KX2-361 is a non-ATP competitive Src inhibitor, demonstrates broad anti-tumor activity both in vitro and in vivo. |
| PC-63476 |
UM-164
c-Src/p38 inhibitor
|
UM-164 is a movel potent, dual c-Src/p38 with Kd of 2.7 nM (c-Src), potently inhibits both p38α and p38β. |
