| Cat. No. |
Product Name |
Information |
| PC-23531 |
Seratrodast
TXA2 antagonist, Ferroptosis inhibitor
|
Seratrodast (AA2414) is a potent, specific thromboxane A2 (TXA2) receptor antagonist, competitively inhibits the contractile response to U-46619 in guinea pig tracheal and parenchymal strips and dog saphenous vein strips with pA2 values of 7.69, 8.29 and 6.79, respectively, also inhibits ferroptosis. |
| PC-22638 |
Asapiprant
DP1 antagonist
|
Asapiprant (S-555739) is a potent and selective prostaglandin DP1 receptor antagonist with Ki of 0.44 nM, >300-fold selective over EP2 and other prostanoid receptors. |
| PC-22116 |
Travoprost
FP receptor agonist
|
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist with Ki of 52 nM, functional EC50 of 27 nM. |
| PC-22027 |
L-902688
EP4 agonist
|
L-902688 (L-902,688) is a potent, selective and orally active EP4 receptor agonist with Ki of 0.38 nM and EC50 of 0.6 nM, >4,000-fold selective for EP4 over other EP and prostanoid receptors. |
| PC-21515 |
EP4R antagonist 77
EP4 antagonist
|
EP4R antagonist 77 is the sodium salt of EP4R antagonist 74, a potent, selective EP4 receptor antagonist with Ki of 11.2 nM. |
| PC-21514 |
EP4R antagonist 74
EP4 antagonist
|
EP4R antagonist 74 is a potent, selective EP4 receptor antagonist with Ki of 11.2 nM, shows apparent dissociation constant KB of 16 nM in functional cAMP production-based assays. |
| PC-21493 |
Cicaprost
IP agonist
|
Cicaprost (ZK 96480) is a potent prostacyclin receptor (IP) agonist, causes a concentration-dependent relaxation of the artery with EC50 of 5.8 nM. |
| PC-21315 |
Ramatroban
TxA2 inhibitor
|
Ramatroban (BAY u3405) is a potent selective thromboxane A2 (TxA2) antagonist with IC50 of 14 nM, also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding. |
| PC-21314 |
AZD1981
DP2 (CRTh2) inhibitor
|
AZD1981 is a potent and selective CRTh2 (DP2) antagonist with pIC50 of 8.4 (human recombinant DP2), with no significant affinity towards recombinant human DP1 receptors. |
| PC-21037 |
TPST-1495
EP2/EP4 antagonist
|
TPST-1495 (TPST1495) is a potent, selective, orally available dual EP2/EP4 PGE2 receptor antagonist with IC50 of 17.21/3.24 nM, respectively. |
| PC-20855 |
L001
EP4 antagonist
|
L001 is a potent and selective EP4 antagonist with cAMP IC50 of 7.29 nM, impairs pancreatic cancer migration and invasion. |
| PC-20852 |
AMX12006
EP4 antagonist
|
AMX12006 (AMX-12006) is a potent, selective, orally active antagonist of prostaglandin E2 (PGE2) receptor 4 (EP4) with IC50 of 4.3 nM in cAMP assays, shows no activity against EP1, EP2, EP3 receptors. |
