L-902688 | EP4 agonist | Probechem Biochemicals

Chemical Structure : L-902688

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L-902688 (L-902,688, L902688)

货号: PC-22027Not For Human Use, Lab Use Only.

L-902688 (L-902,688) is a potent, selective and orally active EP4 receptor agonist with Ki of 0.38 nM and EC50 of 0.6 nM, >4,000-fold selective for EP4 over other EP and prostanoid receptors.

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生物&药学活性

L-902688 (L-902,688) is a potent, selective and orally active EP4 receptor agonist with Ki of 0.38 nM and EC50 of 0.6 nM, >4,000-fold selective for EP4 over other EP and prostanoid receptors.

物理化学性质&存储条件

分子量	419.48
分子式	C21H27F2N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5R)-5-[(1E,3R)-4,4-Difluoro-3-hydroxy-4-phenyl-1-buten-1-yl]-1-[6-(2H-tetrazol-5-yl)hexyl]-2-pyrrolidinone

参考文献

1. Young, R.N., et al. Heterocycles. 2004, 64, 437-445.

2. Lai YJ, et al. Int J Mol Sci. 2018 Mar 3;19(3). pii: E727.

L-902688 (L-902,688, L902688)

生物&药学活性

物理化学性质&存储条件

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L-902688 (L-902,688, L902688)

生物&药学活性

物理化学性质&存储条件

参考文献

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