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首页-小分子抑制剂&激动剂-GPCR-Prostaglandin Receptor-Bimatoprost
Bimatoprost

Chemical Structure : Bimatoprost

CAS No.: 155206-00-1

Bimatoprost (Lumigan, AGN 192024, AGN192024)

货号: PC-24011Not For Human Use, Lab Use Only.

Bimatoprost (AGN 192024) is a prostaglandin analog and prostaglandin FP receptor agonist with Ki of 6.3 uM, reduces intraocular pressure by regulating scleral and trabecular outflow.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bimatoprost (AGN 192024) is a prostaglandin analog and prostaglandin FP receptor agonist with Ki of 6.3 uM, reduces intraocular pressure by regulating scleral and trabecular outflow.

物理化学性质&存储条件

分子量 415.57
分子式 C25H37NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)-N-ethylhept-5-enamide

参考文献

1. Brubaker RF, et al. Am J Ophthalmol. 2001 Jan;131(1):19-24.

2. Sharif NA, et al. Eur J Pharmacol. 2001 Dec 7;432(2-3):211-3.

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