| Cat. No. |
Product Name |
Information |
| PC-45844 |
Senicapoc
KCa3.1 inhibitor
|
Senicapoc (ICA-17043) is a potent, selective Gardos channel (KCa3.1) blocker that blocks Ca(2+)-induced rubidium flux from human RBCs (IC50=11 nM) and inhibits RBC dehydration (IC50=10-50 nM). |
| PC-42381 |
GAL-021
BKCa inhibitor
|
GAL-021 is a respiratory stimulant that acts as a potent calcium-activated potassium (BKCa, KCa1.1) channel blocker blocker. |
| PC-46030 |
Dronedarone
Potassium channel inhibitor, USP11 inhibitor
|
Dronedarone (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats. |
| PC-45962 |
Dronedarone hydrochloride
|
Dronedarone hydrochloride (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats. |
| PC-45472 |
Azimilide dihydrochloride
hERG inhibitor
|
Azimilide dihydrochloride is a class ΙΙΙ antiarrhythmic agent that blocks hERG channel; blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively. |
| PC-45471 |
Azimilide
hERG inhibitor
|
Azimilide (NE-10064) is a class ΙΙΙ antiarrhythmic agent that blocks hERG channel, blocks HERG channel at 0.1 and 1 Hz with IC50s of 1.4 uM and 5.2 uM respectively. |
| PC-47402 |
Quinidine
|
A class I antiarrhythmic agent (Ia) that works by blocking the fast inward sodium current (INa). |
| PC-26897 |
Zinc13732787
KCNQ1/Kv7.1 inhibitor
|
Zinc13732787 is a selective inhibitor of KCNQ1/Kv7.1 potassium channel, without affecting KCNQ2/KCNQ3. |
| PC-26855 |
VU0521426
Kv3.1 channel inhibitor
|
VU0521426 (VU426) is a potent, selective Kv3.1 channel inhibitor with IC50 of 4.3 uM, suppresses Kv3.1 activity413through a state-dependent mechanism consistent with stabilization of non-conducting channel states. |
| PC-26570 |
CHET3
TASK-3 agonist
|
CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels, including TASK-3 homomers and TASK-3/TASK-1 heteromers, displayspotent analgesic effects. |
| PC-26491 |
KCa3.1-IN-1
KCa3.1 inhibitor
|
KCa3.1-IN-1 is a selective small-molecule extracellular inhibitor of KCa3.1 channel (KCNN4) with IC50 of 43.1 uM in duplicate whole-cell patch clamp recordings. |
| PC-26490 |
GLA-1-1
BK channel agonist
|
GLA-1-1 is a small-molecule agonist of large-conductance Ca²⁺-activated K⁺ (BK) channels with EC50 of 3.4 uM, induces autophagy flux by promoting autophagosome-lysosome fusion. |
