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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-Pim

Request The Product List ofPim Pim

Cat. No. Product Name Information
PC-45605

PIM-447

Pim inhibitor

PIM-447 (LGH-447) is a highly potent and selective inhibitor of pan-Pim with IC50s of 6/18/9 pM for Pim/1/2/3 respectively.
PC-23346

Hispidulin

Pim-1 inhibitor, MNK2 inhibitor

Hispidulin (Dinatin) is a natural flavone with a broad spectrum of biological activities, inhibits Pim-1 and MNK2 with IC50 of 1.7 uM and 252 nM respectively, also inhibits COMT.
PC-22796

AZD1208

Pim inhibitor

AZD1208 is a potent and selective, ATP-competitive pan-Pim kinase inhibitor with IC50 of 0.4/5.0/1.9 nM for Pim-1/2/3, respectively.
PC-22079

INCB053914 phosphate

pan-Pim inhibitor

INCB053914 (Uzansertib) phosphate is a novel potent, and selective ATP-competitive, pan-PIM kinase inhibitor with IC50 of 0.24/30.0/0.12 nM for PIM1/2/3, respectively.

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