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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-Pim-Sophoridine
Sophoridine

Chemical Structure : Sophoridine

CAS No.: 6882-68-4

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Sophoridine

货号: PC-27840Not For Human Use, Lab Use Only.

Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens with anticancer efficacy, inhibits HHV-6 replication, inhibits proliferation and migration by targeting PIM1 in breast cancer, inhibits the phosphorylation of ASK1 and activated JNK/p38 MAPK signaling pathway by downregulating PIM1 expression.

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50 mg ￥580 In stock
100 mg ￥880 In stock
250 mg ￥1280 In stock
1 g Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens with anticancer efficacy, inhibits HHV-6 replication, inhibits proliferation and migration by targeting PIM1 in breast cancer, inhibits the phosphorylation of ASK1 and activated JNK/p38 MAPK signaling pathway by downregulating PIM1 expression.

物理化学性质&存储条件

分子量 248.37
分子式 C15H24N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(41S,7aR,13aR,13bR)-Dodecahydro-1H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10(41H)-one

参考文献

1. Qavi HB, et al. Phytother Res. 2002 Mar;16(2):154-6.

2. Dai L, et al. ChemMedChem. 2024 Jan 15;19(2):e202300467.

3. Chen L, et al. Pharm Biol. 2025 Dec;63(1):503-523.

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