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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-Pim-Pim1/AKK1-IN-1
Pim1/AKK1-IN-1

Chemical Structure : Pim1/AKK1-IN-1

CAS No.: 1093222-27-5

Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor)

货号: PC-42554Not For Human Use, Lab Use Only.

Pim1/AKK1-IN-1 is a potent, multikinase inhibitor with Kd of 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.

规格 价格 库存 数量
5 mg ¥1980 In stock
10 mg ¥2880 In stock
25 mg ¥4280 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pim1/AKK1-IN-1 is a potent, multikinase inhibitor with Kd of 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.

物理化学性质&存储条件

分子量 339.3501
分子式 C20H13N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Pyridinecarboxamide, N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-

参考文献

1. Bamborough P, et al. J Med Chem. 2008 Dec 25;51(24):7898-914.

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