GDC-0339 |CAS:1428569-85-0 Probechem Biochemicals

Chemical Structure : GDC-0339

CAS No.: 1428569-85-0

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GDC-0339 (GDC0339)

货号: PC-45110Not For Human Use, Lab Use Only.

GDC-0339 is a potent, orally bioavailable pan-Pim kinase inhibitor with Ki values of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively.

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5 mg	￥4580	In stock
10 mg	￥7280	In stock
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生物&药学活性

GDC-0339 is a potent, orally bioavailable pan-Pim kinase inhibitor with Ki values of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively.

物理化学性质&存储条件

分子量	465.4952
分子式	C20H22F3N7OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 52 mg/mL
Chemical Name/SMILES	4-Thiazolecarboxamide, 5-amino-N-[5-[(4R,5R)-4-amino-5-fluorohexahydro-1H-azepin-1-yl]-1-methyl-1H-pyrazol-4-yl]-2-(2,6-difluorophenyl)-

参考文献

1. Takahashi RH, et al. Drug Metab Dispos. 2017 Aug 8. pii: dmd.117.076786.

GDC-0339 (GDC0339)

生物&药学活性

物理化学性质&存储条件

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GDC-0339 (GDC0339)

生物&药学活性

物理化学性质&存储条件

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