HJ-PI01

Chemical Structure : HJ-PI01

CAS No.: 6192-43-4

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货号: PC-24209Not For Human Use, Lab Use Only.

HJ-PI01 is a novel small molecule inhibitor of Pim2, inhibits Pim-2 and induces apoptosis and autophagy in MDA-MB-231 cells.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥2880	In stock
100 mg		Get quote

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生物&药学活性

HJ-PI01 is a novel small molecule inhibitor of Pim2, inhibits Pim-2 and induces apoptosis and autophagy in MDA-MB-231 cells.
HJ-PI01 displayed excellent inhibitory activity of up to 76.5% at a 1 μmol/L concentration in MDA-MB-231 cells.
HJ-PI01 induces autophagic death in MDA-MB-231 cells
HJ-PI01 induces death receptor-dependent and mitochondrial apoptosis
HJ-PI01 (40 mg/kg) significantly inhibited tumor growth in xenograft mouse model using MDA-MB-231 cells.

物理化学性质&存储条件

分子量	225.25
分子式	C14H11NO2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(10H-Phenoxazin-10-yl)ethan-1-one

参考文献

1. Zhao YQ, et al. Acta Pharmacol Sin. 2016 Sep;37(9):1237-50.

HJ-PI01

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物理化学性质&存储条件

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HJ-PI01

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物理化学性质&存储条件

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