| Cat. No. |
Product Name |
Information |
| PC-49369 |
TH470
LIMK inhibitor
|
TH470 (TH-470) is a potent, highly selective type II LIMK1/2 inhibitor with cellular IC50 of 9.8 and 13 nM, respectively. |
| PC-38206 |
LMTK3 inibitor C28
LMTK3 inhibitor
|
LMTK3 inibitor C28 is a potent, ATP-competitive small-molecule inhibitor of lemur tyrosine kinase 3 (LMTK3) with IC50 of 67 nM. |
| PC-35851 |
TH-257
LIMK1/2 inhibitor
|
TH-257 (TH257) is a potent, selective, allosteric inhibitor of LIMK1 and LIMK2 with IC50 of 84 nM for LIMK1 and 39 nM for LIMK2 in a RapidFire MS assay. |
| PC-35249 |
LIMK1 and 2 dual inhibitor 1
LIMK1/2 inhibitor
|
LIMK1 and 2 dual inhibitor 1 (LIMK1/2-IN-1) is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM). |
| PC-35194 |
SR7826
LIMK1 inhibitor
|
SR7826 is a potent and selective LIM kinase (LIMK) inhibitor with IC50 of 43 nM (LIMK1), displays >100-fold selectivity over ROCK1 and ROCK2, as well as JNK kinases (>400-fold). |
| PC-43141 |
LX7101
LIMK/ROCK inhibitor
|
LX7101 is a potent, dual LIMK and ROCK inhibitor with IC50 of 4.3/32//69/32/ nM for LIMK2/LIMK1/ROCK1/ROCK2, respectively. |
| PC-60271 |
R-10015
LIMK1 inhibitor
|
R-10015 (R10015) is a potent, selective inhibitor of human LIMK1 with IC50 of 38 nM. |
| PC-70101 |
CRT-0105950
LIMK inhibitor
|
CRT-0105950 (CRT0105950) is a novel potent LIMK inhibitor with IC50 of 0.3 nM and 1 nM for LIMK1 and LIMK2, respectively. |
| PC-70100 |
CRT-0105446
LIMK inhibitor
|
CRT-0105446 (CRT0105446) is a novel potent LIMK inhibitor with IC50 of 8 nM and 32 nM for LIMK1 and LIMK2, respectively. |
| PC-70099 |
Pyr1
LIMK inhibitor
|
Liminib (Pyr-1) is a novel potent, selective, cell permeable and ATP competitive LIMK inhibitor. |
| PC-70098 |
LIMK-IN-14
LIMK inhibitor
|
LIMK-IN-14 is a potent, selective LIMK inhibitor with IC50 of 0.9 nM and 0.5 nM and 1.2 nM for LIMK1 and LIMK2, respectively. |
| PC-70097 |
LIMK-IN-22j
LIMK inhibitor
|
LIMK-IN-22j (LIMK-IN-1) is a potent, selective LIMK inhibitor with IC50 of 3.2 nM and 1.2 nM for LIMK1 and LIMK2, respectively. |
