LIMK1 and 2 dual inhibitor 1|CAS:2215049-71-9 Probechem Biochemicals

Chemical Structure : LIMK1 and 2 dual inhibitor 1

加入收藏

LIMK1 and 2 dual inhibitor 1 (LIMK1/2-IN-1)

货号: PC-35249Not For Human Use, Lab Use Only.

LIMK1 and 2 dual inhibitor 1 (LIMK1/2-IN-1) is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

LIMK1 and 2 dual inhibitor 1 (LIMK1/2-IN-1) is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM).
inhibits p-c-ofilin at Ser3 site, suppresses cell proliferation of MV-411 cell of with IC50 of 1-5 uM.

物理化学性质&存储条件

分子量	610.63
分子式	C28H21F3N6O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)-5-(2-(phenylamino)pyrimidin-4-yl)thiazol-2-yl)-N-methylacetamide

参考文献

1. US Patent WO 2018055097.

LIMK1 and 2 dual inhibitor 1 (LIMK1/2-IN-1)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

LIMK1 and 2 dual inhibitor 1 (LIMK1/2-IN-1)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.