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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-LIM Kinase (LIMK)-TH470
TH470

Chemical Structure : TH470

CAS No.: 2834739-51-2

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TH470 (TH-470)

货号: PC-49369Not For Human Use, Lab Use Only.

TH470 (TH-470) is a potent, highly selective type II LIMK1/2 inhibitor with cellular IC50 of 9.8 and 13 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TH470 (TH-470) is a potent, highly selective type II LIMK1/2 inhibitor with cellular IC50 of 9.8 and 13 nM, respectively.
TH470 showed excellent selectivity in a comprehensive scanMAX kinase selectivity panel.

物理化学性质&存储条件

分子量 605.728
分子式 C30H31N5O5S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2-(N-benzyl-4-(N-phenylsulfamoyl)benzamido)ethyl)-2-isobutyramidothiazole-5-carboxamide

参考文献

1. Hanke T, et al. J Med Chem. 2022 Oct 13;65(19):13264-13287. 

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