| Cat. No. |
Product Name |
Information |
| PC-73225 |
NC114
KLF5 inhibitor
|
NC114 is a small molecule targeting cancer-associated KLF5 transcription factor, decreases the KLF protein but not mRNA levels of KLF in vitro. |
| PC-73043 |
SR18662
KLF5 inhibitor
|
SR18662 (SR 18662) is a small-molecule compound that inhibits KLF5 (IC50=4.4 nM), inhibits growth of colorectal cancer in vitro and in vivo. |
| PC-35076 |
APTO-253 hydrochloride
KLF4 inducer
|
APTO-253 is a small molecule inducer of KLF4, stabilizes G-quadruplex DNA and reduces MYC mRNA expression and protein levels. |
| PC-35075 |
APTO-253
KLF4 inducer
|
APTO-253 (LOR-253) is a small molecule inducer of KLF4, stabilizes G-quadruplex DNA and reduces MYC mRNA expression and protein levels. |
| PC-60426 |
YD-277
KLF5 inhibitor
|
YD-277 is a novel small molecule KLF5 inhibitor derived from ML264, demonstrates >10-fold enhanced efficacy in multiple cancer cell lines with IC50 of 1.5-10 uM. |
| PC-45778 |
ML-264
KLF5 inhibitor
|
ML-264 (ML 264) is a potent, selective of KLF5 expression inhibtor, withour effect on kinases associated with the KLF5 pathway. |
| PC-23146 |
KLF2 activator C-6
KLF2 activator
|
KLF2 activator C-6 is a small molecule KLF2 activator, effectively induces downstream Nos3 expression and suppresses NF-kB activation in glomerular endothelial cells, improves albuminuria and glomerulopathy in db/db and BTBR ob/ob mice. |
| PC-22991 |
FZU-00,004
KLF5 inhibitor
|
FZU-00,004 is a small molecule inhibitor of Krüppel-like Factor 5 (KLF5), inhibits KLF5 expression, significantly suppresses TNBC tumor cell growth in vitro and in vivo. |
