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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Kruppel-like Factor (KLF)-KLF2 activator C-6
KLF2 activator C-6

Chemical Structure : KLF2 activator C-6

CAS No.:

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KLF2 activator C-6

货号: PC-23146Not For Human Use, Lab Use Only.

KLF2 activator C-6 is a small molecule KLF2 activator, effectively induces downstream Nos3 expression and suppresses NF-kB activation in glomerular endothelial cells, improves albuminuria and glomerulopathy in db/db and BTBR ob/ob mice.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

KLF2 activator C-6 is a small molecule KLF2 activator, effectively induces downstream Nos3 expression and suppresses NF-kB activation in glomerular endothelial cells, improves albuminuria and glomerulopathy in db/db and BTBR ob/ob mice.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Min L, et al. J Am Soc Nephrol. 2024 Oct 9. doi: 10.1681/ASN.0000000000000498.

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