| Cat. No. |
Product Name |
Information |
| PC-35650 |
CR4056
Imidazoline I2 receptor agonist
|
CR4056 (CR 4056, CR-4056) is a novel, orally active imidazoline-2 receptor (I2R) ligand/agonist with binding IC50 of 596 nM, also selectively inhibits the enzymatic activity of MAO-A with IC50 of 202.7 nM. |
| PC-60740 |
2-BFI hydrochloride
Imidazoline I2 receptor agonist
|
2-BFI hydrochloride (RX801077) is a highly potent, selective imidazoline I2 receptor agonist with Ki of 9.8 nM. |
| PC-23257 |
LNP911
I1R ligand
|
LNP911 is a potent, selective I1 imidazoline receptor (I1R) agonist with Ki of 0.2 nM, without affinity against α2ARs. |
| PC-23256 |
LNP630
I1R agonist
|
LNP630 is a potent, selective I1 imidazoline receptor (I1R) agonist with Ki of 0.93 nM, without affinity against α2ARs, decreases blood pressure. |
| PC-23255 |
S23515
I1R agonist
|
S23515 is a potent, selective I1 imidazoline receptor (I1R) ligand with Ki of 6.4 nM, with no affinity against α2ARs. |
| PC-23253 |
S23757
I1R antagonist
|
S23757 is a potent, selective I1 imidazoline receptor (I1R) antagonist with Ki of 5.3 nM, with no affinity against α2ARs. |
| PC-23252 |
Rilmenidine phosphate
I1R agonist
|
Rilmenidine phosphate is a potent, selective and orally active I1 imidazoline receptor (I1R) agonist with 83.1 nM, displays some selectivity for I1Rs over α2ARs, shows antihypertensive effect. |
| PC-23251 |
Rilmenidine
I1R agonist
|
Rilmenidine is a potent, selective and orally active I1 imidazoline receptor (I1R) agonist with 83.1 nM, displays some selectivity for I1Rs over α2ARs, shows antihypertensive effect. |
| PC-23248 |
LNP509
I1R agonist
|
LNP509 is a potent, selective peripherally acting I1 imidazoline receptor (I1R) agonist with Ki of 537 nM, improves glucose tolerance and insulin sensitivity. |
| PC-23247 |
LNP599
Imidazoline I1 receptor agonist
|
LNP599 is a potent, selective I1 imidazoline receptor (I1Rs) agonist with Ki of 3.2 nM, >3000-fold selective over α2-adreergic receptors. |
