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首页-小分子抑制剂&激动剂-GPCR-Imidazoline Receptor-Rilmenidine
Rilmenidine

Chemical Structure : Rilmenidine

CAS No.: 54187-04-1

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Rilmenidine

货号: PC-23251Not For Human Use, Lab Use Only.

Rilmenidine is a potent, selective and orally active I1 imidazoline receptor (I1R) agonist with 83.1 nM, displays some selectivity for I1Rs over α2ARs, shows antihypertensive effect.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Rilmenidine is a potent, selective and orally active I1 imidazoline receptor (I1R) agonist with 83.1 nM, displays some selectivity for I1Rs over α2ARs, shows antihypertensive effect.

物理化学性质&存储条件

分子量 180.25
分子式 C10H16N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(Dicyclopropylmethyl)-4,5-dihydrooxazol-2-amine

参考文献

1. Gasparik V, et al. J Med Chem. 2015 Jan 22;58(2):878-87.

2. Reid JL. Rilmenidine: a clinical overview. Am J Hypertens. 2000;13(6 Pt 2):106S-111S.

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