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首页-小分子抑制剂&激动剂-GPCR-Imidazoline Receptor-LNP599
LNP599

Chemical Structure : LNP599

CAS No.: 1404051-77-9

LNP599 (LNP-599)

货号: PC-23247Not For Human Use, Lab Use Only.

LNP599 is a potent, selective I1 imidazoline receptor (I1Rs) agonist with Ki of 3.2 nM, >3000-fold selective over α2-adreergic receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LNP599 is a potent, selective I1 imidazoline receptor (I1Rs) agonist with Ki of 3.2 nM, >3000-fold selective over α2-adreergic receptors.

物理化学性质&存储条件

分子量 259.17
分子式 C12H16Cl2N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-Chloro-2-methylphenyl)-4-methylpyrrolidin-2-imine Hydrochloride

参考文献

1. Fellmann L, et al. J Pharmacol Exp Ther. 2013 Sep;346(3):370-80.

2. Gasparik V, et al. J Med Chem. 2015 Jan 22;58(2):878-87.

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