γ-secretase (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-22490	Dibenzazepine γ-secretase inhibitor	Dibenzazepine (YO-01027, DBZ) is a potent γ-secretase inhibitor with IC50 values of 2.92 and 2.64 nM for Notch and APPL cleavage, respectively, exhibits potent inhibiting activity against SPP in vitro and in vivo through the interaction of Val223 in SPP.
PC-60155	γ-secretase modulator 14a	A potent, selective, orally active γ-secretase modulator with Aβ42 IC50 of 39 nM.

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