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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Xanthine Oxidase (XAO)

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Cat. No. Product Name Information
PC-20360

Febuxostat

Xanthine oxidase inhibitor

Febuxostat (TEI-6720) is a potent xanthine oxidase/xanthine dehydrogenase (XO) inhibitor, inhibit bovine milk XO, and mouse liver and rat liver XO with IC50 of 1.4, 1.8 and 2.2 nM, respectively.
PC-20359

Niraxostat

Xanthine oxidase inhibitor

Niraxostat (Y-700) is a potent, long-lasting, orally effective xanthine oxidase (XO) inhibitor with IC50 of 5.8 nM, exhibits potent and long-lasting hypouricemic effect in rat model of hyperuricemia.
PC-20358

Topiroxostat

XOR inhibitor

Topiroxostat (FYX-051, FYX051) is potent xanthine oxidoreductase (XOR) inhibitor with IC50 of 5.3 nM.
PC-38682

Tigulixostat

XAO inhibitor

Tigulixostat (LC350189) is a novel selective xanthine oxidase (XAO) inhibitor under clinical development for the management of hyperuricemia.
PC-47187

Benzbromarone

TMEM16A inhibitor

Benzbromarone (NSC 85433, MJ10061) is a small molecule inhibitor of Eyes Absen (EYA) protein tyrosine phosphatase activity (IC50=8.3 uM, EYA3), exhibits selectivity for EYA over PTP1B.
PC-22859

CC15009

XOR inhibitor

CC15009 is a potent, specific xanthine oxidoreductase (XOR) inhibitor, inhibits XOR-catalyzed uric acid synthesis in vitro with IC50 of 0.237 nM.

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