| Cat. No. |
Product Name |
Information |
| PC-45716 |
MP-A08
SphK inhibitor
|
MP-A08 is a first-in-class, highly selective, ATP competitive sphingosine kinase (SphK) inhibitor (Ki of 6.9/27 uM for SK2/SK1). |
| PC-27898 |
DDI-4
ASR/MOF activator
|
DDI-4 is a dual activator of nematode membranous organelle fusion (MOF) and mouse acrosome reaction (ASR), triggers exocytotic sperm remodeling not only in worms but also in mice. |
| PC-25323 |
ZFP-B34
SphK1/2 inhibitor
|
ZFP-B34 is a potent, dual inhibitor of sphingosine kinase 1/2 (SphK1/2), effectively inhibits cell proliferation, cell cycle progression, and migration in TNBC cells. |
| PC-23349 |
Safingol
SphK inhibitor, PKC inhibitor
|
Safingol (L-threo-dihydrosphingosine) is a putative inhibitor of sphingosine kinase (SphK) and PKCalpha (PKCα), suppresses growth of human oral squamous cell carcinoma (SCC) cells, significantly inhibits PKC isoforms. |