| Cat. No. |
Product Name |
Information |
| PC-28387 |
Taprenepag isopropyl
EP2 receptor agonist
|
Taprenepag isopropyl (PF-04217329) is the prodrug of Taprenepag (CP-544326), a potent and selective prostaglandin EP2 receptor agonist with IC50 of 10 nM and EC50 of 2.8 nM. |
| PC-28386 |
Taprenepag
EP2 receptor agonist
|
Taprenepag (CP-544326) is the active acid metabolite of Taprenepag isopropyl (PF-04217329) and potent and selective prostaglandin EP2 receptor agonist with IC50 of 10 nM and EC50 of 2.8 nM. |
| PC-28235 |
DT-9081
EP4 antagonist
|
DT-9081 is a potent, selective and orally bioavailable antagonist of prostaglandin E2 receptor EP4 (EP4R), counteracts tumor-driven immunosuppression. |
| PC-28214 |
KF-0210
EP4 antagonist
|
KF-0210 is a potent, selective and oral EP4 receptor antagonist with binding IC50 of 18.6 nM, shows >500-fold selectivity over other prostaglandin receptors, including EP1, EP2, EP3, IP, DP1, and FP. |
| PC-27721 |
GR63799
EP3 agonist
|
GR63799X (GR63799) is a potent and selective prostanoid EP3 receptor agonist. |
| PC-27720 |
DG041
EP3 antagonist
|
DG-041 (DG041) is a potent and selective prostanoid EP3 receptor antagonist with IC50 of 4.6 nM and 8.1 nM in binding and FLIPR assay, respectively. |
| PC-27537 |
HTL0039732
EP4 antagonist
|
HTL0039732 is a potent, selective and orally bioavailable E-type prostanoid receptor 4 (EP4) antagonist, blocks signalling through prostaglandin E2 receptor EP4, enhances immune response against tumours that typically resist current immunotherapies. |
| PC-27072 |
Evatanepag
EP2 receptor agonist
|
Evatanepag (CP-533536, CP-533,536) is a highly selective and potent functional EP2 receptor agonist with high affinity to rat EP2 receptor (IC50=50 nM), is >50-fold more selective over EP4 receptor subtype. |
| PC-24436 |
ACT-1002-4271
EP2/EP4 antagonist
|
ACT-1002-4271 is a potent, selective dual EP2/EP4 antagonist with IC50 of 6 nM/3 nM for hEP2/hEP4 respectively in cAMP-based activity assays. |
| PC-35836A |
PGN 9856-isopropyl ester
EP2 receptor agonist
|
PGN 9856-isopropyl ester is the isopropyl ester, which is a potent, selective prostaglandin EP2 receptor agonist with pKi of > 8.3. |
| PC-22116 |
Travoprost
FP receptor agonist
|
Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist with Ki of 52 nM, functional EC50 of 27 nM. |
| PC-35836D |
d4-PGN9856
EP2 receptor agonist
|
d4-PGN9856 is a d4-labelled PGN-9856, which is a potent, selective prostaglandin EP2 receptor agonist. |
