HMG-CoA Reductase (HMGCR) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-49778	Apomine HMGCR inhibitor	Apomine (SR-45023A) is an oral biphosphonate antineoplastic compound inhibiting HMG-CoA reductase, induces HMG-CoA reductase degradation with EC50 of 0.88 uM.
PC-49777	SRK2128 HMGCR degrader	SRK2128 (SRK 2128) is a highly potent HMG-CoA reductase degrader with EC50 of 84 nM, potently induce degradation of HMG-CoA reductase.
PC-45539	BRD7116 HMGCR inhibitor	BRD7116 selective inhibitor of leukemia stem cells (LSCs) via inhibition of HMG-CoA reductase (HMGCR).
PC-45300	Simvastatin HMGCR inhibitor	Simvastatin (MK-733) is a potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with Kd of 0.1-0.2 nM.
PC-45305	Rosuvastatin HMGCR inhibitor	Rosuvastatin (ZD-4522) is a potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with IC50 of 11 nM.
PC-45304	Rosuvastatin calcium HMGCR inhibitor	Rosuvastatin (ZD-4522) calcium is a potent, competitive inhibitor of HMG-CoA reductase (HMGCR) with IC50 of 11 nM.
PC-45230	Mevastatin HMGCR inhibitor	Mevastatin (ML236B) is a hypolipidemic agentt that inhibits HMGCR (HMG-CoA reductase).
PC-46757	Atorvastatin HMGCR inhibitor	Atorvastatin is a competitive inhibitor of HMG-CoA reductase (HMGCR) that acts as a lipid-lowering agent for prevention of events associated with cardiovascular disease.
PC-45201	Atorvastatin hemicalcium HMGCR inhibitor	Atorvastatin hemicalcium is a competitive inhibitor of HMG-CoA reductase (HMGCR) that acts as a lipid-lowering agent for prevention of events associated with cardiovascular disease.
PC-23009	Pravastatin sodium HMGCR inhibitor	Pravastatin (CS-514) sodium is a selective HMG-CoA reductase (HMGCR) inhibitor with IC50 of 5.6 uM against sterol synthesis.
PC-23008	Lovastatin HMGCR inhibitor	Lovastatin is a cell-permeable HMGCR (HMG-CoA reductase) inhibitor, shows cholesterol lowering effect.
PC-21969	Bemfivastatin HMGCR inhibitor	Bemfivastatin (PPD-10558) is an orally active, lipid-lowering 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor for treatment of hypercholesterolemia.

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