Mevastatin (Compactin, ML-236B) | HMGCR inhibitor | Probechem Biochemicals

Chemical Structure : Mevastatin

CAS No.: 73573-88-3

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Mevastatin (Compactin, ML-236B, ML236B)

货号: PC-45230Not For Human Use, Lab Use Only.

Mevastatin (ML236B) is a hypolipidemic agentt that inhibits HMGCR (HMG-CoA reductase).

规格	价格	库存
50 mg	￥580	In stock
100 mg	￥880	In stock
500 mg	￥1980	In stock
1 g		Get quote

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生物&药学活性

Mevastatin (Compactin, ML-236B) is a hypolipidemic agentt that inhibits HMGCR (HMG-CoA reductase).
Mevastatin (ML236B) inhibits isoprenoid biosynthesis, blocks protein isoprenylation and reduces plasma cholesterol level.
Mevastatin (ML236B) also blcoks autolysosome maturation, stimulates LBH589-induced cell death in TNBC cells.

物理化学性质&存储条件

分子量	390.5131
分子式	C23H34O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-

参考文献

1. Lin Z, et al. Oncotarget. 2017 Mar 14;8(11):17833-17848.

2. Brown M, et al. Br J Cancer. 2012 May 8;106(10):1689-96.

3. Zhang S, et al. Anticancer Drugs. 2010 Aug;21(7):678-86.

Mevastatin (Compactin, ML-236B, ML236B)

生物&药学活性

物理化学性质&存储条件

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Mevastatin (Compactin, ML-236B, ML236B)

生物&药学活性

物理化学性质&存储条件

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