Cat. No. |
Product Name |
Information |
PC-23810 |
Tamsulosin
TMEM16A inhibitor
|
Tamsulosin ((R)-(-)-YM12617 free base) is an inhibitor of α1-adrenergic receptor, also demonstrates significant antiosteoporotic effects by inhibiting calcium-activated chloride channel TMEM16A. |
PC-23489 |
ClC-1 inhibitor Compound A-3
ClC-1 channel inhibitor
|
ClC-1 inhibitor Compound A-3 is a specific inhibitor of skeletal muscle-specific chloride ion (Cl-) channel ClC-1 with IC50 of 2.3 uM for reduction in the Cl- driven membrane conductance (Gm). |
PC-22008 |
NMD670 sodium
ClC-1 inhibitor
|
NMD670 (NMD-670) sodium salt is a potent, specific and orally bioavailable ClC-1 chloride channel inhibitor with EC50 of 1.6 uM, restores muscle function in rat models of myasthenia gravis (MG). |