IAA-94 |CAS:54197-31-8 Probechem Biochemicals

Chemical Structure : IAA-94

CAS No.: 54197-31-8

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IAA-94 (IAA94)

货号: PC-43155Not For Human Use, Lab Use Only.

IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of epithelial chloride channels that binds channels in bovine kidney cortex microsomes with Ki of 1 uM.

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1380	In stock
50 mg	￥2280	In stock
100 mg		Get quote

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生物&药学活性

IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of epithelial chloride channels that binds channels in bovine kidney cortex microsomes with Ki of 1 uM.
IAA-94 significantly suppresses IGF-I-induced VSMC proliferation, also blocks cell swelling evoked glutamate release from primary microglia and MLS-9 cells.
IAA-94 effectively reduces IFNgamma-induced NO production in microglial BV2 cells.

物理化学性质&存储条件

分子量	357.2284
分子式	C17H18Cl2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Acetic acid, 2-[[(2R)-6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl]oxy]-

参考文献

1. Landry DW, et al. J Gen Physiol. 1987 Dec;90(6):779-98.

2. Cheng G, et al. Cardiovasc Res. 2007 Jan 1;73(1):198-207.

3. Schlichter LC, et al. Channels (Austin). 2011 Mar-Apr;5(2):128-37.

4. Kjaer K, et al. Brain Res. 2009 Jul 24;1281:15-24.

IAA-94 (IAA94)

生物&药学活性

物理化学性质&存储条件

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IAA-94 (IAA94)

生物&药学活性

物理化学性质&存储条件

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