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首页-小分子抑制剂&激动剂-GPCR-Bradykinin Receptor

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Cat. No. Product Name Information
PC-20273

FR-190997

B2R agonist

FR-190997 (FR190997) is a potent, nonpeptide bradykinin (BK) B2 receptor agonist binding IC50 of 1.5 nM (displaced [3H]-BK binding to B2 receptors in guinea-pig ileum membranes).
PC-47507

Bradykinin

Bradykinin receptor ligand

Bradykinin is a 9-amino acid peptide (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg).
PC-45267

Icatibant

B2R antagonist

Icatibant (HOE 140, JE-049) is a potent, selective and specific antagonist of bradykinin B2 receptor (B2R) with IC50 and Ki of 1.07 nM and 0.798 nM respectively.
PC-25718

SSR240612

B1R antagonist

SSR240612 is a potent, selective, non-peptide antagonist of bradykinin (BK) B(1) receptor, inhibits binding of [(3)H]Lys(0)-des-Arg(9)-BK to B(1) receptor in human fibroblast MRC5 and to recombinant human B(1) receptor expressed in human embryonic kidney cells with Ki of 0.48 and 0.73 nM, respectively.
PC-23553

R715

B1R antagonist

R715 is a potent, selective bradykinin B1 receptor (B1R) antagonist.

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