URAT1 (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-20286	Lesinurad URAT1 inhibitor	Lesinurad (RDEA594) is a potent selective urate anion transporter 1 (URAT1) inhibitor with IC50 of 3.5 and 81 µM for human and rat URAT1, respectively.
PC-20285	HR011303 URAT1 inhibitor	Ruzinurad (HR011303) is a potent, highly selective and orally available urate transporter 1 (URAT1) inhibitor, significantly decrease serum uric acid levels superior to Lesinurad.
PC-60708	UR-1102 URAT1 inhibitor	UR-1102 is a novel potent and selective, orally active URAT1 inhibitor with Ki of 57 nM, 130 and 42-fold selectivity over OAT1 and OAT3, respectively.
PC-60041	Dotinurad URAT1 inhibitor	Dotinurad (FYU-981) is a potent and selective urate transporter 1 (URAT1) inhibitor with IC50 of 37.2 nM.
PC-45065	Verinurad URAT1 inhibitor	Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with IC50 of 25 nM.
PC-23087	Lingdolinurad URAT1 inhibitor	Lingdolinurad (ABP-671, ABP671) is a novel selective and potent URAT1 inhibitor, reduces reabsorption of uric acid (UA) at the renal proximal tubule, prevents gout flare-ups.

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