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首页-小分子抑制剂&激动剂-Epigenetics-Sirtuin

Request The Product List ofSirtuin Sirtuin

Cat. No. Product Name Information
PC-21715

UBCS373

Sirtuin 4 inhibitor

UBCS373 (Sirt4 inhibitor 69) is a highly isoform selective inhibitor of mitochondrial deacylase Sirtuin 4 (Sirt4) with IC50 of 16 uM.
PC-21714

UBCS385

Sirtuin 4 inhibitor

UBCS385 (Sirt4 inhibitor 60) is a potent, selective inhibitor of mitochondrial deacylase Sirtuin 4 (Sirt4) with IC50 of 0.9 uM.
PC-21306

SirReal1.2

Sirtuin 2 inhibitor

SirReal1.2 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.12 uM.
PC-21305

SirReal1.1

Sirtuin 2 inhibitor

SirReal1.1 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.16 uM.
PC-21146

SIRT2 inhibitor 33a

Sirtuin 2 inhibitor

SIRT2 inhibitor 33a is a potent, specific Sirtuin 2 (SIRT2) inhibitor with IC50 of 1.0 uM, no activity against SIRT1 and SIRT3 (IC50>100 uM).
PC-21145

SIRT2 inhibitor 33i

Sirtuin 2 inhibitor

SIRT2 inhibitor 33i is a potent, specific Sirtuin 2 (SIRT2) inhibitor with IC50 of 0.57 uM, no activity against SIRT1 and SIRT3 (IC50>100 uM).
PC-21061

ADTL-SA1215

SIRT3 activator

ADTL-SA1215 is a small-molecule activator of SIRT3 with EC50 of 0.21 uM, specifically activates SIRT3 but not SIRT1, SIRT2, and SIRT5.
PC-21027

LC-0296

SIRT3 inhibitor

LC-0296 (LC0296) is a selective sirtuin-3 (SIRT3) inhibitor with IC50 of 3.6 uM, shows 20- and 10-fold selectivity over SIRT1 and SIRT2 respectively.
PC-21014

FLS-359

SIRT2 inhibitor

FLS-359 (FLS-359) is a selective, allosteric inhibitor of sirtuin 2 (SIRT2) deacetylase activity with IC50 of 3 uM, shows no activity against SIRT1 and SIRT3, exhibits broad-spectrum antiviral activity.
PC-72774

SIRT2 inhibitor 56

SIRT2 inhibitor

SIRT2 inhibitor 56 is a potent selective SIRT2 inhibitor with IC50 of 780 nM.
PC-72773

SIRT2 inhibitor 55

SIRT2 inhibitor

SIRT2 inhibitor 55 is a potent and selective SIRT2 inhibitor with IC50 of 250 nM.
PC-72772

SIRT3 inhibitor 8

SIRT3 inhibitor

SIRT3 inhibitor 8 is a SIRT3 selective inhibitor with IC50 of 6 uM, 6.8- and 5.3-fold selectivity for SIRT3 versus SIRT1 and SIRT2.

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