AK-7 |CAS:420831-40-9 Probechem Biochemicals

Chemical Structure : AK-7

CAS No.: 420831-40-9

加入收藏

AK-7 (SIRT2 inhibitor AK-7, AK7)

货号: PC-45037Not For Human Use, Lab Use Only.

AK-7 is a potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 15.5 uM.

规格	价格	库存
10 mg	￥980	In stock
25 mg	￥1580	In stock
50 mg	￥2480	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

AK-7 is a potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 15.5 uM.
AK-7 reduces cholesterol in cultured naive neuronal cells and brain slices from wild-type mice.
AK-7 shows neuroprotective activity in Huntington's disease mouse models, and reduces cholesterol in neuronal models.

物理化学性质&存储条件

分子量	437.3506
分子式	C19H21BrN2O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, N-(3-bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-

参考文献

1. Taylor DM, et al. ACS Chem Biol. 2011 Jun 17;6(6):540-6.

2. Chopra V, et al. Cell Rep. 2012 Dec 27;2(6):1492-7.

3. Biella G, et al. J Alzheimers Dis. 2016 Jun 30;53(3):1193-207.

AK-7 (SIRT2 inhibitor AK-7, AK7)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

AK-7 (SIRT2 inhibitor AK-7, AK7)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.