| Cat. No. |
Product Name |
Information |
| PC-26328 |
Funopixant
P2X3 antagonist
|
Funopixant is a potent, selective P2X3 receptor antagonist with IC50 of 32.45 nM for hP2X3. |
| PC-26169 |
PSB-OR-2020
P2X4 antagonist
|
PSB-OR-2020 is a potent, selective P2X4 receptor antagonist, inhibits ATP-induced Ca2+ influx by in 1321N1 astrocytoma cells stably transfected with the human P2X4 receptor with IC50 of 6.32 nM, >300-fold selective over P2X1, P2X2, P2X3, and P2X7. |
| PC-26168 |
A-317491
P2X3 antagonist
|
A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors with Ki of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. |
| PC-26167 |
PSB-1011
P2X2 antagonist
|
PSB-1011 is a potent, moderately selective rat P2X2 receptor antagonist with IC50 of 79 nM, weakly inhibits P2X1 and P2X3 receptors and shows no activity against P2X4 and P2X7 receptors. |
| PC-26166 |
PSB-2014
P2X1 antagonist
|
PSB-2014 is a potent, selective and competitive P2X1 receptor (P2X1R) with IC50 of 23.1 nM, weakly inhibits P2X4, P2X7 and shows no activity against P2X2, P2X3 receptors. |
| PC-26165 |
PSB-2001
P2X1 antagonist
|
PSB-2001 is a potent, selective and competitive P2X1 receptor (P2X1R) with IC50 of 19.2 nM, weakly inhibits P2X4, P2X7 and shows no activity against P2X2, P2X3 receptors. |
| PC-26164 |
NF023
P2X1 antagonist
|
NF023 hexasodium is a potent, selective and competitive P2X1 receptor (P2X1R) antagonist with IC50 of 0.21 uM (human P2X1), >100-fold selective over P2X3, P2X2, and P2X4 receptors. |
| PC-26163 |
BzATP triethylammonium salt
P2X receptors agonist
|
BzATP triethylammonium salt is a broad P2X receptors agonist with pEC50 values of 8.74, 5.26, 7.10, 7.50, 6.19, 6.31, 5.33 for P2X1, P2X2, P2X3, P2X2/3, P2X4 and P2X7, respectively. |
| PC-26162 |
PSB-15417
P2X4 antagonist
|
PSB-15417 is a potent, specific P2X4 receptor (P2X4R) antagonist with IC50 of 21.9 nM and 37 nM for human and rat P2X4 receptor, shows limited activity against P2X1, P2X2, P2X3 and P2X7 receptors (All IC50>2 uM). |
| PC-26161 |
PSB-12062
P2X4 antagonist
|
PSB-12062 is a potent, specific P2X4 receptor antagonist with IC50 of 1.38 uM, >35-fold selective over P2X1, P2X2, P2X3 and P2X7 receptors. |
| PC-26159 |
PSB-0704
P2X4 antagonist
|
PSB-0704 is a potent, allosteric P2X4 receptor inhibitor with IC50 of 12.5 and 0.07 uM for human wt P2X4 and P2X4-E307T receptor mutant. |
| PC-26158 |
Cibacron Blue
P2X receptor modulator
|
Cibacron Blue is a non-selective allosteric modulator of P2X2, P2X3, and P2X4 receptors, shows anti-inflammatory and antiarthritic, anti-cancer activites, also inhibits R46 β-lactamase with Ki of 1.2 uM. |
