Keap1-Nrf2 (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-21180	NRF2 inhibitor R16 NRF2 inhibitor	NRF2 inhibitor R16 is a novel mutated KEAP1 (mKEAP1)-selective NRF2 inhibitor, binds KEAP1-mutated proteins (G333C mKEAP1, Kd=2.7 uM) and restores their interaction with NRF2, leading to proteasome-dependent NRF2 degradation.
PC-21171	Spinosin Nrf2/HO-1 activator	Spinosyn is a C-glycoside flavonoid isolated from the seeds of Zizyphus jujube with neuroprotective effects, inhibits Aβ1-42 production and aggregation via activating Nrf2/HO-1 pathway.
PC-20558	Keap1-Nrf2 inhibitor 25 Keap1-Nrf2 inhibitor	Keap1-Nrf2 inhibitor 25 is a potent, orally bioavailable Keap1-Nrf2 protein-protein interaction (PPI) inhibitor with IC50 of 89 nM.

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