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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Keap1-Nrf2-CDDO-EA
CDDO-EA

Chemical Structure : CDDO-EA

CAS No.: 932730-51-3

CDDO-EA (CDDO ethyl amide;RTA405;TP319;RTA 405;TP 319;RTA-405;TP-319)

货号: PC-42917Not For Human Use, Lab Use Only.

CDDO-EA (DDO ethyl amide, RTA405) is a potent Nrf2 activator that upregulates Nrf2 expression and resulted in translocation of Nrf2 into the nucleus.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CDDO-EA (DDO ethyl amide, RTA405) is a potent Nrf2 activator that upregulates Nrf2 expression and resulted in translocation of Nrf2 into the nucleus.

物理化学性质&存储条件

分子量 518.7299
分子式 C33H46N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Oleana-1,9(11)-dien-28-amide, 2-cyano-N-ethyl-3,12-dioxo-

参考文献

1. Alabran JL, et al. Cancer Biol Ther. 2008 May;7(5):709-17.

2. Neymotin A, et al. Free Radic Biol Med. 2011 Jul 1;51(1):88-96.

3. Liby K, et al. Cancer Res. 2007 Mar 15;67(6):2414-9.

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