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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Glucocorticoid receptor (GR)

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Cat. No. Product Name Information
PC-45279

Cortisone acetate

Cortisone acetate (Cortisone 21-acetate) is a synthetic glucocorticoid corticosteroid and corticosteroid ester.
PC-45278

Cortisone

Cortisone is a pregnane (21-carbon) steroid hormone, one of the main hormones released by the adrenal gland in response to stress.
PC-45281

Prednisolone

GR agonist

Prednisolone is a potent, orally active corticosteroid and a glucocorticoid, shows Ki of 5.4 nM and 0.26 nM for Glucocorticoid receptor (GR) and Mineralocorticoid receptor (MR), produces transactivation at both the GR (EC50=24.3 nM) and MR (EC50=11.8 nM), with no detectable transactivation of the PR.
PC-45987

Cortodoxone

GR antagonist

Cortodoxone (11-Deoxycortisol, Cortexolone) is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone), exhibits corticosteroid binding characteristics, including DNA binding.
PC-28298

Ciclesonide

GR modulator

Ciclesonide (RPR251526) is synthetic glucocorticoid with low glucocorticoid receptor affinity, Ciclesonide is activated to desisobutyryl-ciclesonide (des-CIC) to exhibit potent anti-inflammatory activity.

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