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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Glucocorticoid receptor (GR)-Ciclesonide
Ciclesonide

Chemical Structure : Ciclesonide

CAS No.: 126544-47-6

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Ciclesonide (RPR251526)

货号: PC-28298Not For Human Use, Lab Use Only.

Ciclesonide (RPR251526) is synthetic glucocorticoid with low glucocorticoid receptor affinity, Ciclesonide is activated to desisobutyryl-ciclesonide (des-CIC) to exhibit potent anti-inflammatory activity.

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25 mg ￥750 In stock
50 mg ￥1150 In stock
100 mg ￥1750 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ciclesonide (RPR251526) is synthetic glucocorticoid with low glucocorticoid receptor affinity, Ciclesonide is activated to desisobutyryl-ciclesonide (des-CIC) to exhibit potent anti-inflammatory activity.

物理化学性质&存储条件

分子量 540.69
分子式 C32H44O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)-, (11β,16α)-

参考文献

1. Belvisi MG, et al. J Pharmacol Exp Ther. 2005 Aug;314(2):568-74.

2. Stoeck M, et al. J Pharmacol Exp Ther. 2004 Apr;309(1):249-58.

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