| Cat. No. |
Product Name |
Information |
| PC-26032 |
PF-03550096
CB2 agonist
|
PF-03550096 is a potent, selective orally active cannabinoid receptor 2 (CB2) agonist with Ki of 7.9 nM and 47 nM for human and rat CB2 receptors respectively. |
| PC-26031 |
MDA77
CB2 inverse agonist
|
MDA77 is a potent selective cannabinoid receptor 2 (CB2) inverse agonist with EC50 of 5.82 nM at human CB2, with no activity at CB1, inhibits the effect of MDA7 (CB2 agonist) in animal model of neuropathic pain. |
| PC-26030 |
GW842166X
CB2 agonist
|
GW842166X (GW-842,166X) is a potent and selective cannabinoid receptor 2 (CB2) agonist with IC50 of 63 and 91 nM for human and rat CB2, respectively. |
| PC-26029 |
MDA7
CB2 agonist
|
MDA7 is is a potent, selective agonist for cannabinoid receptor 2 (CB2) with EC50 of 128 nM and 67.4 nM for human and rat in GTPγ[35S] functional assays, suppresses neuropathic nociception. |
| PC-26028 |
VU6077967
CB2 agonist
|
VU6077967 is a potent, selective, and CNS-penetrant agonist of cannabinoid receptor 2 (CB2) with EC50 of 8.6 nM (rCB2), inactive against rCB1. |
| PC-25525 |
BI-5756
CETP inhibitor, CB1 agonist
|
BI-5756 is a cholesteryl ester transfer protein (CETP) inhibitor, also is a potent agonist of cannabinoid receptor 1 (CB1R, CB1) with IC50 of 0.966 uM in cell-based radioligand binding assay using CP55940. |
| PC-25356 |
ISAM-CG557
CB2 receptor agonist
|
ISAM-CG557 is a potent, selective, and functionally biased CB2 receptor (CB2R) agonist with binding Ki of 54.6 nM, with negligible binding to CB1R, shows strongly biased toward MAPK signaling. |
| PC-25116 |
CB1 receptor antagonist QD13
CB1 antagonist
|
CB1 receptor antagonist QD13 is a selective antagonist cannabinoid type 1 (CB1) receptor (CB1R), effectively blocks the receptor activation by the agonists. |
| PC-25022 |
Selonabant
CB1R antagonist
|
Selonabant (ANEB-001, V24343) is potent, selective cannabinoid type 1 receptor (CB1, CB1R) antagonist. |
| PC-24486 |
Z8526711350
CB1R agonist
|
Z8526711350 (CB1R agonist '1350) is a potent, specific agonist of cannabinoid-1 receptor (CB1R) with Ki of 0.95 nM, is a full agonist of CB1R-mediated Gi/o signaling. |
| PC-24481 |
VIP36
CB1 agonist
|
VIP36 is a potent, selective and highly peripherally restricted Gi-biased agonist of cannabinoid receptor type 1 (CB1) with Ki of 22 nM in radioligand competition assays, exerts analgesic efficacy through peripheral CB1 receptors and shows limited analgesic tolerance. |
| PC-24424 |
BNS808
CB1R antagonist
|
BNS808 is a potent, peripherally selective cannabinoid-1 receptor (CB1R) antagonist with Ki values of 0.7 nM for both mouse and human CB1R and IC50 of 0.8 nM (hCB1R), >2000-fold selective over CB2R. |
