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首页-小分子抑制剂&激动剂-GPCR-Cannabinoid Receptor-MDA77
MDA77

Chemical Structure : MDA77

CAS No.: 1103774-21-5

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MDA77

货号: PC-26031Not For Human Use, Lab Use Only.

MDA77 is a potent selective cannabinoid receptor 2 (CB2) inverse agonist with EC50 of 5.82 nM at human CB2, with no activity at CB1, inhibits the effect of MDA7 (CB2 agonist) in animal model of neuropathic pain.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MDA77 is a potent selective cannabinoid receptor 2 (CB2) inverse agonist with EC50 of 5.82 nM at human CB2, with no activity at CB1, inhibits the effect of MDA7 (CB2 agonist) in animal model of neuropathic pain.

物理化学性质&存储条件

分子量 365.43
分子式 C21H23N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzoic acid, (2Z)-2-(1,2-dihydro-6-methoxy-2-oxo-1-pentyl-3H-indol-3-ylidene)hydrazide

参考文献

1. Philippe Diaz, et al. J Med Chem. 2009 Jan 22;52(2):433-44.

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