| Cat. No. |
Product Name |
Information |
| PC-27912 |
Ro 41-0960
COMT inhibitor, Na+/K+-ATPase inhibitor
|
Ro 41-0960 is a potent and selective, CNS-penetrant, orally active inhibitor of catechol-O-methyltransferase (COMT), also is a Na+/K+-ATPase inhibitor with IC50 of 17.9 uM and 10.3 uM for purified enzyme and microsomal preparations. |
| PC-23347 |
OR486
COMT inhibitor
|
OR486 (3,5-Dinitrocatechol, OR-486) is a potent, selective catechol-O-methyltransferase (COMT) inhibitor with IC50 of 12 nM. |
| PC-35901 |
QO IIR
COMT inhibitor
|
QO IIR is a reversible, tight-binding inhibitor inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 320 nM. |
| PC-35791 |
Nebicapone
COMT inhibitor
|
Nebicapone (BIA 3-202, BIA3-202) is a potent, long-acting, reversible and competitive peripheral inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 3.7 nM for rat brain COMT, much less potent for liver COMT with IC50 of 696 nM. |
| PC-35459 |
Neluxicapone
COMT inhibitor
|
Neluxicapone is a potent, selective inhibitor of catechol-O-methyltransferase (COMT).. |
| PC-45228 |
Tolcapone
COMT inhibitor
|
Tolcapone (Ro 40-7592) selective, potent and reversible nitrocatechol-type inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 700 nM. |
| PC-27913 |
U-0521
COMT inhibitor, FTO inhibitor
|
U-0521 is a potent and selective catechol O-methyltransferase (COMT) inhibitor with IC50 of 6 uM. |
| PC-27365 |
Entacapone
COMT inhibitor, FTO inhibitor
|
Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor with IC50 values of 10 nM, 20 nM, and 160 nM for COMT from rat brain, erythrocytes and liver respectively. |
