Ro 41-0960 | COMT inhibitor, Na+/K+-ATPase inhibitor | Probechem Biochemicals

Chemical Structure : Ro 41-0960

CAS No.: 125628-97-9

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Ro 41-0960 (Ro41-0960)

货号: PC-27912Not For Human Use, Lab Use Only.

Ro 41-0960 is a potent and selective, CNS-penetrant, orally active inhibitor of catechol-O-methyltransferase (COMT), also is a Na+/K+-ATPase inhibitor with IC50 of 17.9 uM and 10.3 uM for purified enzyme and microsomal preparations.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥2980	In stock
100 mg		Get quote

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生物&药学活性

Ro 41-0960 is a potent and selective, CNS-penetrant, orally active inhibitor of catechol-O-methyltransferase (COMT), also is a Na+/K+-ATPase inhibitor with IC50 of 17.9 uM and 10.3 uM for purified enzyme and microsomal preparations.

物理化学性质&存储条件

分子量	277.21
分子式	C13H8FNO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3,4-Dihydroxy-5-nitrophenyl)(2-fluorophenyl)methanone

参考文献

1. Percy E, et al. Br J Pharmacol. 1999 Oct;128(3):774-80.

2. Cruz-Cortés C, et al. ChemMedChem. 2026 Sep 14;21(17):e70442.

Ro 41-0960 (Ro41-0960)

生物&药学活性

物理化学性质&存储条件

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Ro 41-0960 (Ro41-0960)

生物&药学活性

物理化学性质&存储条件

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