Pyruvate Kinase (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-23534	ACT001 NF-κB inhibitor, PKM2 activator	ACT001 (dimethylaminomicheliolide, DMAMCL) is a guaianolide sesquiterpene lactone that targets lasminogen activator inhibitor-1 (PAI-1), also is a a nuclear factor-κB (NF-κB) signaling pathway inhibitor and PKM2 activator, effectively inhibits the proliferation of both tamoxifen-sensitive and tamoxifen-resistant cells.
PC-22788	Urolithin C PKL inhibitor	Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion, Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx, also is an allosteric inhibitor of liver-specific isoform of pyruvate kinase (PKL).
PC-22681	PKM2 aggregates inhibitor K27 PKM2 aggregates inhibitor	PKM2 aggregates inhibitor K27 is a small molecule capable of dissolving PKM2 aggregates and alleviating senescence, restores PKM2 enzymatic activity and glycolytic flux, delays aging of naturally and prematurely aged mice.
PC-22680	PKM2 aggregates inhibitor K35 PKM2 aggregates inhibitor	PKM2 aggregates inhibitor K35 is a small molecule capable of dissolving PKM2 aggregates and alleviating senescence, restores PKM2 enzymatic activity and glycolytic flux, delays aging of naturally and prematurely aged mice.

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